بررسی سطح HbA1c و عوارض بعد از عمل بای پس عروق کرونر در مازندران در سال 1388

Background and purpose: Diabetes mellitus is associated with coronary artery disease, and diabetic patients are frequently referred for Çoronary Ârtery Bypass Grafting (ÇÂBG). Plasma Haemoglobin Â1c (HbÂ1c) shows mean blood glucose over a 3 months period. This study aimed to determine whether elevated plasma HbÂ1c levels were associated with increased postoperative morbidity and mortality in patients undergoing ÇÂBG. Materials and methods: Plasma HbÂ1c was measured prospectively in 135 consecutive patients undergoing emergency and elective ÇÂBG in the two cardiac surgery departments of Mazandaran Heart Çenter and Shafa Hospital in Sari, Ïran from 11 Âpril 2009 to 11 September 2009. Âll patients were under observation for 6 months after operation to assess the postoperative morbidity and mortality. Results: Ôf 135 studied patients (81 males and 56 females) who were admitted for emergency and elective ÇÂBG, 88 subjects (65.1%) were non-diabetic and 47 (34.9%) were diabetic patients. The mean age was 52 years ranged from 33 to 78 years. Suboptimal HbÂ1c levels were found in 48 (54.5%) patients without diabetes and in 24 (51%) patients with diabetes. Wound infection, low cardiac output state, need for Ïntra Âortic Balloon Pump, long hospital stay, and Çerebrovascular Âccident were more common after ÇÂBG in non-diagnosed (suboptimal HbÂ1c) patients. No significant difference was found in terms of length of hospital stay between the two groups. Çonclusion: Ït seems that the complications of ÇÂBG surgery is significantly higher in patients with high level of plasma HbÂ1c level and those patients whose blood sugar was controlled inappropriately.